BBC NEWS | Health | Virus used to kill food = bug

From: Subject: BBC NEWS | Health | Virus used to kill food bug Date: Tue, 8 Jul 2003 15:53:26 -0700 MIME-Version: 1.0 Content-Type: multipart/related; boundary="----=_NextPart_000_0187_01C34569.11B20D70"; type="text/html" X-MimeOLE: Produced By Microsoft MimeOLE V6.00.2800.1165 This is a multi-part message in MIME format. ------=_NextPart_000_0187_01C34569.11B20D70 Content-Type: text/html; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable Content-Location: http://news.bbc.co.uk/2/hi/health/2970215.stm BBC NEWS | Health | Virus used to kill food = bug

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Last = Updated: Wednesday, 23 April, 2003, 23:52 GMT 00:52 UK = =20

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Virus used to kill food=20 bug

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The E.coli = bug

Sheep=20 carry a virus which could be harnessed to kill the E.coli = food=20 poisoning bug.=20

The discovery could help eradicate E.coli 0157 in farm = animals,=20 reducing the chance of humans becoming infected with the bug = through=20 the food chain.

Three-quarters of cases can be traced directly back to = livestock,=20 which can harbour the infection without becoming ill.

Meat can become contaminated when the animals are = slaughtered.=20 Manure can also be a source of infection.

Researchers from Evergreen State College in Washington = state were=20 testing antibiotics to see which could eliminate E.coli from = animals.

The first stage was to infect sheep with E.coli. But the = bacteria=20 kept disappearing.

The animals were re-infected three times, but each time, = the=20 bacteria vanished.

'Wipe out'

Scientists discovered that the sheep carried a = bacteria-killing=20 virus, or bacteriaphage, that infects certain E.coli = strains.

Laboratory tests showed the CEV1 phage killed 16 out of = 18 toxic=20 strains of E.coli, but only eight out of 73 harmless = strains.

Further tests in sheep showed the bacteriaphage cut the = number of=20 E.coli present by 99% in two days.

Dr Andrew Brabben, who led the research, hopes his = findings will=20 be help wipe out E.coli in herds and flocks.

He said phages, unlike antibiotics, only attack = particular=20 bacteria.

In addition, antibiotics are expensive and need to be = given to=20 every animal, while only one would need to be infected with = CEV1 for=20 it to be passed to a whole herd.

The phage also appears to continue to reproduce itself = after all=20 the toxic E.coli has been destroyed by replicating itself in = a=20 harmless E.coli strain.

Consequences

Dr Brabben said it was more practical to give the phage = to=20 animals rather than humans.

Destroying E.coli 0157 can release large amounts of its = toxin,=20 which can make a patient's condition worse.

In addition, animal treatments do not have to meet the = same=20 safety standards as in humans.

However, the researchers will have to show that treating = animals=20 with the phage will not affect the delicate balance of flora = in=20 human guts if they are passed on via the food chain.

The research was presented to the Society for General=20 Microbiology meeting and is published in New Scientist = magazine.

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PADDING-LEFT: 5px; FONT-WEIGHT: bold; FONT-SIZE: 10px; PADDING-BOTTOM: = 2px; COLOR: #ffffff; PADDING-TOP: 2px; BACKGROUND-COLOR: #990000 } .avt { FONT-SIZE: 11px } .spb { BORDER-TOP-WIDTH: 1px; BORDER-LEFT-WIDTH: 1px; BORDER-BOTTOM-WIDTH: = 1px; WIDTH: 203px; BACKGROUND-COLOR: #ffffcc; BORDER-RIGHT-WIDTH: 1px } .spbe { BORDER-TOP: 1px dashed; PADDING-BOTTOM: 3px; PADDING-TOP: 3px; = BORDER-BOTTOM: 1px dashed; BACKGROUND-COLOR: #ffff33 } .gnb { BORDER-TOP-WIDTH: 1px; PADDING-LEFT: 5px; BORDER-LEFT-WIDTH: 1px; = BORDER-BOTTOM-WIDTH: 1px; PADDING-BOTTOM: 5px; COLOR: #ffffff; = PADDING-TOP: 5px; BACKGROUND-COLOR: #669933; BORDER-RIGHT-WIDTH: 1px } .tqub { BORDER-TOP-WIDTH: 1px; PADDING-LEFT: 5px; BORDER-LEFT-WIDTH: 1px; = BORDER-BOTTOM-WIDTH: 1px; PADDING-BOTTOM: 5px; COLOR: #000000; = PADDING-TOP: 5px; BACKGROUND-COLOR: #99cccc; BORDER-RIGHT-WIDTH: 1px } .mph { PADDING-LEFT: 5px; FONT-WEIGHT: bold; FONT-SIZE: 10px; PADDING-BOTTOM: = 2px; COLOR: #ffffff; PADDING-TOP: 2px; BACKGROUND-COLOR: #999966 } .formatStyle { WIDTH: 160px } .ddb { BORDER-TOP-WIDTH: 1px; PADDING-LEFT: 5px; BORDER-LEFT-WIDTH: 1px; = FONT-SIZE: 11px; BORDER-BOTTOM-WIDTH: 1px; PADDING-BOTTOM: 5px; COLOR: = #000000; PADDING-TOP: 2px; BACKGROUND-COLOR: #ffffff; = BORDER-RIGHT-WIDTH: 1px } .ddh { FONT-WEIGHT: bold; FONT-SIZE: 10px; COLOR: #000000 } .ddt { FONT-SIZE: 11px; MARGIN-BOTTOM: 5px } TD.sibt { FONT-SIZE: 11px } .sih { PADDING-LEFT: 5px; FONT-WEIGHT: bold; FONT-SIZE: 10px; PADDING-BOTTOM: = 2px; COLOR: #666633; PADDING-TOP: 2px; BACKGROUND-COLOR: #cccc99 } .sibf { MARGIN-LEFT: 5px; BACKGROUND-COLOR: #ffffcc } .sibmg { MARGIN-LEFT: 5px; BACKGROUND-COLOR: #ffde9c } .cap { FONT-WEIGHT: normal; FONT-SIZE: 10px; COLOR: #666666 } .bys { FONT-WEIGHT: bold; FONT-SIZE: 11px; COLOR: #000000 } .byl { FONT-WEIGHT: bold; FONT-SIZE: 11px; COLOR: #666666 } .byd { FONT-SIZE: 11px; COLOR: #000000 } .msd { FONT-WEIGHT: bold; FONT-SIZE: 11px; COLOR: #666666 } .sah { PADDING-LEFT: 5px; FONT-WEIGHT: bold; FONT-SIZE: 10px; PADDING-BOTTOM: = 2px; COLOR: #ffffff; PADDING-TOP: 2px; BACKGROUND-COLOR: #999966 } .sad { FONT-SIZE: 11px; COLOR: #666666 } .snh { PADDING-LEFT: 5px; FONT-WEIGHT: bold; FONT-SIZE: 10px; PADDING-BOTTOM: = 2px; COLOR: #ffffff; PADDING-TOP: 2px; BACKGROUND-COLOR: #999999 } .sng { BACKGROUND-COLOR: #cccccc } .sph { PADDING-LEFT: 5px; FONT-WEIGHT: bold; FONT-SIZE: 10px; PADDING-BOTTOM: = 2px; COLOR: #ffffff; PADDING-TOP: 2px; BACKGROUND-COLOR: #336699 } A.tickl { FONT-WEIGHT: bold; FONT-SIZE: 11px; COLOR: #000099; LINE-HEIGHT: 12px; = FONT-FAMILY: Verdana,Arial,Helvetica,sans-serif; TEXT-DECORATION: none } A.tickl:hover { COLOR: #6666cc; TEXT-DECORATION: none } .ticki { OVERFLOW: hidden; WIDTH: 629px; HEIGHT: 13px } .ticko { PADDING-RIGHT: 0px; BORDER-TOP: #cccccc 1px solid; DISPLAY: block; = PADDING-LEFT: 0px; PADDING-BOTTOM: 4px; MARGIN: 4px 0px 2px; WIDTH: = 629px; PADDING-TOP: 4px; BORDER-BOTTOM: #cccccc 1px solid } .tickls { COLOR: #666666 } .tickh { DISPLAY: none } .psrhb { PADDING-BOTTOM: 2px } .psrht { MARGIN-TOP: 3px; FONT-WEIGHT: bold; FONT-SIZE: 10px; MARGIN-BOTTOM: = 3px; COLOR: #666666 } .pinp { FONT-SIZE: 11px; WIDTH: 160px; FONT-FAMILY: Verdana, Arial, Helvetica } ------=_NextPart_000_0187_01C34569.11B20D70 Content-Type: application/x-javascript Content-Transfer-Encoding: quoted-printable Content-Location: http://newsimg.bbc.co.uk/nol/shared/js/nol.js /*Generic pop up code - please use this only unless you really need = something different*/ function popUpPage(url, parameters, name) { var day =3D new Date(); var pageName =3D name ? name : day.getTime() eval("bbc"+pageName+" =3D = window.open('"+url+"','"+pageName+"','"+parameters+"')"); if (eval("bbc"+pageName) && window.focus) eval("bbc"+pageName).focus(); } /* launch code for avconsole */ function launch_main_player(site) { =09 if (site =3D=3D null) //no site name passed in - have to leave this = check in { = clickmain=3Dwindow.open("http://news.bbc.co.uk/broadband/news_console.stm= ","clickmain","toolbar=3D0,location=3D0,status=3D0,menubar=3D0,scrollbars= =3D0,resizable=3D0,top=3D100,left=3D100,width=3D671,height=3D373"); } else { if (site =3D=3D 'ukfs') { = clickmain=3Dwindow.open("http://news.bbc.co.uk/broadband/news_console.stm= ","clickmain","toolbar=3D0,location=3D0,status=3D0,menubar=3D0,scrollbars= =3D0,resizable=3D0,top=3D100,left=3D100,width=3D671,height=3D373"); } else if (site =3D=3D 'ifs') { = clickmain=3Dwindow.open("/narrowband/static/audio_video/avconsole/ifs/f_n= ews_console.stm","clickmain","toolbar=3D0,location=3D0,status=3D0,menubar= =3D0,scrollbars=3D0,resizable=3D0,top=3D100,left=3D100,width=3D671,height= =3D373"); } } } function getPlatform() { var myUserAgent; myUserAgent =3D navigator.userAgent.toLowerCase(); if ((myUserAgent.indexOf("win") !=3D -1) || = (myUserAgent.indexOf("16bit") !=3D -1)) { return "win"; } =09 if (myUserAgent.indexOf("mac") !=3D -1) { return "mac"; } =20 =09 if (myUserAgent.indexOf("x11") !=3D -1) { return "unx"; } =20 =09 return "other"; } function getBrowserType() { var myUserAgent; var myMajor; myUserAgent=3D navigator.userAgent.toLowerCase(); myMajor=3D parseInt(navigator.appVersion); if( (myUserAgent.indexOf('mozilla')!=3D -1) = &&(myUserAgent.indexOf('spoofer')=3D=3D -1) = &&(myUserAgent.indexOf('compatible') =3D=3D -1) = &&(myUserAgent.indexOf('opera') =3D=3D -1) = &&(myUserAgent.indexOf('webtv') =3D=3D -1) ) { =20 if (myMajor > 3) { return "nav4"; } =09 return "nav"; } =09 if (myUserAgent.indexOf("msie")!=3D -1) { =20 =09 if (myMajor > 3) { return "ie4"; }=20 =09 return "ie"; } // dom compliant browsers are allowed if(document.body.firstChild) return "domCompliant"; return "other"; } function request_launch(site) { if (getPlatform() !=3D "other" &&(getBrowserType() =3D=3D "ie4" || = getBrowserType() =3D=3D "nav4" || getBrowserType() =3D=3D = "domCompliant")) { launch_main_player(site); }=20 else=20 { = self.location.href=3D"/1/shared/bsp/hi/services/help/html/av_console_brow= sers.stm"; } =09 return; } function openWindow(){ var mywin =3D null;var unLoad; var surl =3D = "http://news.bbc.co.uk/hi/english/static/business/data_desktop/mardata/ft= se.stm"; if (!mywin){mywin =3D = window.open(surl,'BBCNewsOnline','toolbar=3D0,location=3D0,directories=3D= 0,status=3D0,menubar=3D0,scrollbars=3D0,resizable=3D0,width=3D370,height=3D= 292'); mywin.location =3D surl; if (mywin.opener =3D=3D null) mywin.opener =3D window;=20 mywin.opener.name =3D "opener"; }else{ if (mywin.closed){=09 mywin =3D null;openWindow(); } if (mywin.focus) mywin.focus(); mywin.location.href =3D surl; } } function popup(url) { day =3D new Date(); id =3D day.getTime(); eval("page" + id + " =3D window.open(url, '" + id + "', = 'toolbar=3D0,location=3D0,directories=3D0,status=3D0,menubar=3D0,scrollba= rs=3D0,resizable=3D0,width=3D370,height=3D220');"); }=20 function popUp(pageurl,width,height,scroll){ day =3D new Date(); id =3D day.getTime(); if (window.screen) { =20 lpos =3D (screen.width/2)-(width/2); =20 hpos =3D (screen.height/2)-(height/2); }else { lpos =3D 1; hpos =3D 1; =09 } =09 eval("bbcnews"+id+" =3D = window.open('"+pageurl+"','"+id+"','toolbar=3D0,scrollbars=3D"+scroll+",l= ocation=3D0,status=3D0,menubar=3D0,resizable=3D0,width=3D"+width+",height= =3D"+height+",left=3D"+lpos+",top=3D"+hpos+"')"); } ------=_NextPart_000_0187_01C34569.11B20D70 Content-Type: application/x-javascript Content-Transfer-Encoding: quoted-printable Content-Location: http://server-uk.imrworldwide.com/a1.js =0A= ------=_NextPart_000_0187_01C34569.11B20D70--