| Title: |
Faculty Member, The Evergreen State College Director of Research, Barlow Scientific, Inc. |
Education: |
| Harvey Mudd College, Claremont, CA |
|
B.S., Chemistry |
|
1964 |
| University of California, Berkeley, CA |
Ph.D., Chemistry (Biophysics) |
1968 |
Employment, Experience, Honors: |
| Research Biochemist |
|
Barlow Scientific, Inc., Olympia, WA |
|
1984-present |
| Member of the Faculty |
Chemistry and Biochemistry, The Evergreen State College, Olympia, WA |
1972-present |
| Visiting Professor |
Dept. of Chemistry, Univ. of Washington, Seattle, WA |
1987-1988 |
| Visiting Scientist |
Center for Process Analytical Chemistry, Dept. of Chemistry, Univ. of Washington, Seattle, WA |
1986-1987, 1988-1992 |
| Visiting Professor |
Harvey Mudd College, Claremont, CA |
1980-1981 |
| Assistant Professor |
Dept. of Chemistry, Reed College, Portland, OR |
1968-1972 |
| Research Chemist |
Lawrence Radiation Lab., Berkeley, CA |
1968 |
Societies: |
| AAAS (1964), Sigma Xi (1968), Society for Applied Spectroscopy (1989), Biophysical Society (1995), Biomedical Engineering Society (1995) |
Patents: |
| U.S. Patent No. 5,422,730, "Automated Optical Detection of Tissue Perfusion by Microspheres", June 1995. |
Recent Publications: |
- Barlow, C.H., Rorvik, D.A. and Kelly, J.J. (1988) Epicardial oxygen/metabolism by Pd porphyrin and NADH imaging. J. Cell Bio. 107:213a.
- Kelly, J.J., Rorvik, D.A., Richmond, K.N. and Barlow, C.H. (1989) Videofluorometer for imaging tissue metabolism. Rev. Sci. Instr. 60:3498-3502.
- Kelly, J.J., Barlow, C.H., Jinguji, T.M. and Callis, J.B. (1989) Prediction of gasoline octane numbers by near infrared spectroscopy in the spectral range 680-1235 nm. Anal. Chem. 61:313-320.
- Phalen, M.K., Barlow, C.H., Kelly, J.J., Jinguji, T.M. and Callis, J.B. (1989) Measurement of caustic and caustic brine by spectroscopic detection of the hydroxide ion in the wavelength range 700-1150 nm. Anal. Chem. 61:1419-1424.
- Rorvik, D.A., Kelly, J.J., Burns, D.H. and Barlow, C.H. (1989) Imaging cytochrome oxidation in hypothermically stored rat kidneys. IEEE/EMBS 11:622-623.
- Barlow, C.H. and Kelly, J.J. (1990) Metabolic spectroscopy for monitoring electromagnetic medical techniques. In Emerging Electromagnetic Medical Technology, (eds. O'Connor, M.E., Bentall, R.H.C. and Monahan, J.C.), Springer Verlag, pp. 103-123.
- Kelly, J.J and Callis, J.B. (1990) Fast, non-destructive analytical procedure for the simultaneous estimation of the major classes of hydrocarbon constituents of finished gasoline. Anal. Chem. 62:1444-1451.
- Kelly, J.J., Kelly, K.A. and Barlow, C.H. (1991) Myoglobin oxygen binding curves determined by phosphorescence quenching. Appl. Spectrosc. 45:1177-1182.
- Barlow, C.H., Kelly, K.A. and Kelly, J.J. (1992) Simultaneous determination of hemoglobin and myoglobin oxygen binding curves by spectral curve fitting. Appl. Spectrosc. 46:758-763.
- Aldridge, P.A., Burns, D.H., Kelly, J.J. and Callis, J.B. (1993) Monitoring of a polymerization reaction using on-line SW-NIR spectroscopy. Process Control and Quality 4:155-160.
- Lysaght, M.J., Kelly, J.J. and Callis, J.B. (1993) Rapid spectroscopic determination of percent aromatics, percent saturates and freezing point of JP-4 aviation fuel. Fuel 72:623-631.
- Mayes, D.A., Kelly, J.J. and Callis, J.B. (1993) Non-invasive monitoring of chemical reactions with shortwave near-infrared spectroscopy. In NIR-92 Proceedings, (eds. Hildrum, K.I. et al) Ellis Horwood Ltd, UK.
- Barlow, C.B., Bailey, E.J., Mundy, B.J., Pratt, D.S., Sloan, W.C., Kelly, K.A. and Kelly, J.J (1993) Epicardial hemprotein oxygenation and redox state through spectral curve fitting. FASEB J. 7: A1074.
- Aldridge, P.A., Burns, D.H., Kelly, J.J. and Callis, J.B. (1994) Non-invasive monitoring of methyl methacrylate polymerization using SW-NIR spectroscopy. Anal. Chem. 65:3581-3585.
- Kelly, J.J., Kelly, K.A. and Barlow, C.H. (1995) Tissue temperature by near-infrared spectroscopy. In Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media, (eds. Chance, B and Alfano, R.R.) SPIE, 2389:818-828.
- Kelly, J.J., Holloway, G.A., Jr., Rorvik, D.A., Reinbold, T.R. and Barlow, C.H. Skin flap circulation: a comparison of fluorescein videofluorometry and laser Doppler detection. Submitted to Plastic and Reconstructive Surgery.
- Kelly, J.J., Ewen, J.R. and Barlow, C.H. Regional blood flow measurments from fluorescent microsphere images. In preparation for submission to Review of Scientific Instruments.
- Barlow, C.H., Bailey, E., Kelly, K.A. and Kelly, J.J. Monitoring epicardial oxygen gradients with reflectance spectra. In preparation for submission to American Journal of Physiology.
- Kelly, J.J., Bailey, E., Rorvik, D.A. and Barlow, C.B. Skin flap viability evaluated by fluorescein videofluorometry. In preparation for submission to Plastic and Reconstructive Surgery.
- Barlow, C.H., Kelly, K.A., Bailey, E. and Kelly, J.J. (1997) Reflectance measurement of heart muscle oxygenation. In Oxygen Transport to Tissue XX, (eds. Hudetz, A.G. and Bruley, D.), Plenum Press.
- Kelly, J.J., Barlow, C.H., Kelly, K.A. and Ewen, J. (1997) Sublobular distribution of cytochromes in cold-stored rat liver. In Oxygen Transport to Tissue XX, (eds. Hudetz, A.G. and Bruley, D.), Plenum Press.
- Barlow, C.H., Rorvik, D.A. and Kelly, J.J. (1998) Imaging epicardial oxygen. Annals of Biomedical Engineering 26(1):76-85.
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| Abstracts and Presentations: |
- Ott, J., Brewster, S., Barlow, C.H. and Kelly, J.J. "NADH fluorescence changes in response to spreading depression". Society for Neuroscience, November 1987.
- Kelly, J.J. "Prediction of quality parameters of gasolines from near-infrared spectra using multivariate statistics". West Coast Exchange Group of the ASTM, November 1988.
- Lysaght, M.J., Kelly, J.J. and Callis, J.B. "Field testing and quality evaluation of aviation fuels by near infrared spectroscopy and multivariate statistics". Pittsburgh Conference, March 1990.
- Callis, J.B., Kelly, J.J. and Mayes, D.M. "Non-Invasive Short Wave Near Infrared Sensing Applied to Process Analysis". Federation of Analytical Chemistry and Spectroscopy Societies, October 1990.
- Conley, K.E., Barlow, C.H., Kelly, J.J., Rorvik, D.A. and Kushmerick, M.J. "Redox changes with work in rat heart". Biophysical Society, February 1991.
- Lysaght, M.J., Kelly, J.J. and Callis, J.B. "Rapid spectroscopic determination of percent aromatics, percent saturates and freezing point in JP-4 aviation fuel". Federation of Analytical Chemistry and Spectroscopy Societies, October 1991.
- Aldridge, P.K., Wu, C., Burns, D.H., Kelly, J.J. and Callis, J.B. "Monitoring of a polymerization reaction using on-line SW-NIR spectroscopy". Federation of Analytical Chemistry and Spectroscopy Societies, October 1991.
- Barlow, C.H., Kelly, K.A. and Kelly, J.J. "Epicardial oxygen/metabolism by Pd porphyrin and NADH imaging". Biophysical Society, February 1992.
- Conley, K.E., Barlow, C.H., Kelly, J.J., Rorvik, D.A. and Kushmerick, M.J. "NAD(P)H redox in rat heart: fluorescence imaging and spectroscopy". Biophysical Society, February 1992.
- Glenny, R.W., Bernard, S., Barlow, C.B., Kelly, J.J. and Robertson, H.T. "Imaging the spatial distribution of pulmonary perfusion across scales of resolution". The Biomedical Engineering Society, November 1994. Ann. Biomed. Eng. 22:13, 1994.
- Glenny, R.W., Bernard, S., Barlow, C.B., Kelly, J.J. and Robertson, H.T. "Spatial distribution of pulmonary blood flow at a microscopic scale of resolution". Am. J. Repsir. Crit. Care Med. 151:A518, 1995.
- Barlow, C.H., Kelly, K.A., Bailey, E. and Kelly, J.J. "Measurement of heart muscle oxygenation". The American College of Sports Medicine, September 1995.
- Barlow, C.H., Ewen, J., Glenny, R.W. and Kelly, J.J. "Fluorescence imaging for measurement of regional blood flow". The American Physiological Society, April 1996.
- Barlow, C.H., Ewen, J., Glenny, R.W. and Kelly, J.J. "Microsphere imaging system". Fluorescent Microsphere Resource Center, August 1996.
- Ewen, J., Barlow, C.H., Vaupel, J., Glenny, R.W. and Kelly, J.J. "Heterogeneity of Flow and Metabolism in Rat Heart During Graded Ischemia". Fluorescent Microsphere Resource Center, August 1996.
- Rorvik, D.A., Kelly, J.J., Glenny, R.W. and Barlow, C.H. "Fluorescent Microsphere Counting For Flow Measurements". Fluorescent Microsphere Resource Center, August 1996.
- Kelly, J.J., Kelly, K.A. and Barlow, C.H. "Sublobular Distribution of Cytochromes in Cold-Stored Liver". 25th Annual Conference of the International Society on Oxygen Transport to Tissue, August 1997.
- Barlow, C.H., Kelly, K.A., Bailey, E. and Kelly, J.J. "Reflectance Measurement of Heart Muscle Oxygenation". 25th Annual Conference of the International Society on Oxygen Transport to Tissue, August 1997.
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