POISONOUS AND HALLUCINOGENIC MUSHROOMS
by Michael W. Beug Email: firstname.lastname@example.org
The Evergreen State College, Olympia WA
Conocybe filaris, also known as Pholiotina filaris,
is another species that can contain lethal levels of the amanitins and
also grows mixed in with similar-sized Psilocybes. Like all of the mushrooms
shown so far, the critical feature is that the onset of symptoms will be
delayed for 6-24 hours and then after a period of intense gastrointestinal
distress the patient will appear to recover before having a very serious,
potentially fatal, reappearance of symptoms coupled with elevated liver
enzymes. The amatoxins inhibit RNA polymerase, which transcribes m-RNA.
They affect the gastrointestinal epithelium, centrilobular hepatocytes
and nephrocytes in the proximal convoluted tubes. Kidney and liver failure
follows with bleeding and neurologic dysfunction. There are a number of
important serum tests available to doctors to assist in tracking treatments.