Thursday, June 8, 2000

SESSION III: Structure

Chair: Eleanor Spicer

11:10 – 11:30 a.m.

THE ROLE OF BASEPLATE PROTEIN gp29 IN BACTERIOPHAGE T4 TAIL ASSEMBLY

Yuefei Lou et. al.

11:30 – 11:50 a.m.

RECOGNITION OF RECEPTOR LIPOPOLYSACCHARIDES

Minoru Inagaki et al.

LUNCH

Thursday, June 8, 2000

SESSION IV: Recombination and Phage Tools

Chair: Ian Molineux

7:30 - 7:50 p.m.

A BIPARTITE BACTERIOPHAGE T4 SOC AND HOC RANDOMIZED PEPTIDE DISPLAY LIBRARY: DETECTION AND ANALYSIS OF PHAGE T4 TERMINASE (gp17) AND LATE SIGMA FACTOR (gp 55) INTERACTION

Lindsay Black

7:50 - 8:10 p.m.

TRANSGENE INTEGRATION IN SCHIZOSACCHAROMYCES POMBE MEDIATED BY THE STREPTOMYCES BACTERIOPHAGE PhiC31 SITE-SPECIFIC RECOMBINATION SYSTEM

Lynn Thomason et al.

8:10 - 8:30 p.m.

REQUIREMENT OF PHAGE LAMBDA RECOMBINATION FUNCTIONS FOR PHAGE-PROPHAGE MARKER RESCUE

Sidney Hayes et al.

COFFEE BREAK AND POSTER SESSION

Thursday, June 8, 2000

POSTER SESSION: 8:30 P.M. - ?

IN VITRO SELECTION OF RNA APTAMERS THAT BIND INTACT BACTERIOPHAGE

Timothy Dean et al.

PARTIAL SEQUENCE OF PSEUDOMONAS putida PHAGE gh-1 USING SHOTGUN SEQUENCING STRATEGY, EVIDENCE FOR RELATIONSHIP TO THE T7 GROUP

Irina Kovalyova et al.

DEVELOPMENT OF THERAPEUTICS FOR THE TREATMENT OF BACTERIAL INFECTIONS USING LADS

David Schofield

DEVELOPMENT OF THERAPEUTICS FOR THE TREATMENT OF BACTERIAL INFECTIONS USING LADS

Laura Kasman

TREATMENT OF EXPERIMENTAL INFECTIONS IN EMBRYONATED HEN EGGS AND MICE

Laura Kasman et al.

THE COMPLETED SEQUENCE OF THE GENOME OF SALMONELLA typhimurium PHAGE P22

Andrew M. Kropinski

BIOLOGICAL CONTROL OF ERWINA amylovora WITH BACTERIOPHAGES

J.J. Gill et al.

THE FREQUENCY OF LYSOGENY AND POLYLYSOGENY IN BACTERIA ISOLATED FROM NORTHERN ADRIATIC SEA

David Stopar et al.

ANTIBIOTIC-INDUCED "PSEUDOLYSOGENY": IMPLICATIONS FOR ANTIBIOTIC/ PHAGE COMBINATION THERAPY

Richard Weld

EFFECTS OF HOST PHYSIOLOGY ON THE INTRACELLULAR GROWTH OF PHAGE T7

Lingchong You

TESTING THE MOBILITY OF FIMBRIAL OPERONS BY PHAGE INDUCTIONS EXPERIMENTS

Hojabr Dezfulian et al.

ELABORATION OF THE NEW MEDICINAL-PROPHYLACTIC BACTERIOPHAGES AGAINST PURULENT INFECTIONS

Inga Giorgadze

Friday, June 9, 2000

SESSION V: Gene Expression

Chair: Rich Calendar

9:00 - 9:20 a.m.

TRANSLATIONAL REPRESSOR regA PROTEINS FROM PHAGE T4 AND RB69 HAVE CONSERVED RNA BINDING DOMAINS BUT DIFFERENT RNA BINDING SPECIFICITIES

Eleanor Spicer et al.

9:20 - 9:40 a.m.

ROLE OF mRNA SECONDARY STRUCTURE IN THE TRANSLATIONAL INITIATION REGION OF GENE 25 OF T4-TYPE BACTERIOPHAGES

Rimas Nivinskas

9:40 - 10:00 a.m.

DETERMINANTS FOR DNA BINDING BY A MEMBER OF THE P2 Ogr FAMILY OF ZINC-FINGER TRANSCRIPTION FACTORS

Gail Christie et al.

10:00 – 10:20 a.m.

ORGANIZATION OF THE GENOME OF P1 BACTERIOPHAGE: TRACKING THE DEVELOPMENTAL PROGRAM OF EXPRESSION OF P1 PHAGE GENES

Malgorzata Lobocka et al.

10:20 - 10:40 a.m.

THE CONSERVED Ner FAMILY OF TRANSPOSABLE PHAGES

Michael S. DuBow et al.

COFFEE BREAK

Friday, June 9, 2000

SESSION VI: Lysis

Chair: Donna Duckworth

11:00 – 11:20 a.m.

NEW INSIGHTS ON THE FOUNDING PHENOMENON OF MOLECULAR GENETICS: THE MECHANISM OF LYSIS-INHIBITION

Erian Ramanculov et al.

11:20–11:40 a.m.

DISSECTION OF MOLECULAR EVENTS LEADING TO FORMATION OF THE LAMBDA S HOLIN-DEPENDENT LESION IN THE CYTOPLASMIC MEMBRANE

Udo Bläsi et al.

11:40 – 12 noon:

A PLETHORA OF LYSIS-TIMING

Stephen T. Abedon

LUNCH BREAK

Friday, June 9, 2000

SESSION VII: Phage Therapy

Chair: Lindsay Black

2:15 - 2:35 p.m.

OVERVIEW OF PHAGE THERAPY

Betty Kutter

2:35 - 2:55 p.m.

CHARACTERIZATION OF TWO THERAPEUTIC STAPHYLOCOCCAL AND COLI-DYSENTERIAL BACTERIOPHAGES

Revaz Adamia

2:55 - 3:15 p.m.

USE OF VIBRIO vulnificus BACTERIOPHAGE TO PREVENT DISEASE IN A MOUSE MODEL OF INFECTION

Donna Duckworth et al.

COFFEE BREAK

3:30 - 3:50 p.m.

A BACTERIOPHAGE LETHAL AGENT DELIVERY SYSTEM FOR THE TREATMENT OF BACTERIAL INFECTIONS

Caroline Westwater

3:50 - 4:10 p.m.

BIOLOGICAL CONTROL OF ERWINA amylovora WITH BACTERIOPHAGES

J.J. Gill et al.

4:10 - 4:45 p.m.

DEVELOPMENT AND COMMERCIALIZATION OF PHAGE THERAPY IN THE UNITED STATES

Alexander Sulakvelidze et al.

4:45 - 5:30 p.m.

DISCUSSION OF PHAGE THERAPY

Saturday, June 10, 2000

SESSION VIII: Phage Evolution

Chair: Gisela Mosig

9:00 - 9:20 a.m.

STRUCTURAL, GENETIC AND EVOLUTIONARY ANALYSES OF MICROVIRIDAE SCAFFOLDING PROTEINS

Bentley Fane

9:20 - 9:40 a.m.

DARWINIAN EVOLUTION OF THE STRUCTURAL GENE CLUSTER IN SIPHOVIRIDAE?

Harald Bruessow et al.

9:40 - 10:00 a.m.

T-EVEN PHAGES AND THE REAL WORLD

Betty Kutter

10:00 –10:20 a.m.

MOLECULAR ANALYSIS OF LYTIC YERSINIA ENTERO-COLITICA SEROTYPE 0:3-SPECIFIC BACTERIOPHAGE phi-Ye03-12

Maria Pajunen et al.

COFFEE BREAK

10:40 – 11:00 a.m.

LYSOGENIC CONVERSION BY P2-RELATED PHAGES: A NOVEL METHYLASE ENCODED BY PHAGE Wphi

Gail Christie et al.

11:00 – 11:20 a.m.

PARTIAL GENETIC CHARACTERIZATION OF COLIPHAGE LG1

Lawrence Goodridge

11:20 – 11:40 a.m.

CHARACTERISATION OF THE LYSOGENIC PHAGE IN SALMONELLA ENTERICA SEROVAR TYPHIMURIUM

Princess Mmolawa et al.

11:40– 12:00 noon

BACTERIOPHAGE PHYLOGENETICALLY RELATED TO T4 INFECT A WIDE RANGE OF HOST BACTERIAL SPECIES

Mzia Kutaleladze

LUNCH BREAK

Saturday, June 10, 2000

SESSION IX: T4 DNA Replication

Chair: Steve Abedon

2:00 - 2:20 p.m.

EVIDENCE THAT DNA POLYMERASE PROOFREADING CREATES AN OPPORTUNITY FOR MISALIGNMENT MUTAGENESIS. STUDIES OF THE BACTERIOPHAGE T4 DNA POLYMERASE PROOFREADING PATHWAY

Linda Reha-Krantz et al

2:20 - 2:40 p.m.

THE CHARACTERISATION OF A UNIQUE MUTANT OF T4 TOPOISOMERASE THAT IS HYPERSENSITIVE TO A BROAD RANGE OF CLEAVAGE-INDUCING ANTITUMOR AGENTS

Erin O’Reilly et al.

2:40 – 3:00 p.m.

REPAIR OF TOPOISOMERASE-MEDIATED DNA DAMAGE IN BACTERIOPHAGE T4

Brad Stohr

3:00 – 3:20 p.m.

LOADING ENZYMES ONTO ssDNA—T4 PHAGE AND THE RMP

Scott Morrical et al.

COFFEE BREAK

3:40 – 4:00 p.m.

AN UNCONVENTIONAL USE OF ITERONS AT THE PHAGE T4 ORIGIN E OF DNA REPLICATION

Gisela Mosig et al.

4:00 – 4:20 p.m.

PHAGE 54 rl AS A MUTATION-REPORTER GENE

Gerry Carver et al.

4:20 – 4:40 p.m.

THE FIDELITIES OF PHAGE-RB69 DNA POLYMERASES COMPARED IN VIVO AND IN VITRO

Jan Drake et al.

6:30 - ?

DINNER AND CRUISE ON THE ST-LAWRENCE RIVER

Sunday, June 11, 2000

SESSION X: Phage and Pathogenesis

Chair: David Coombs

9:00 – 9:20 a.m.

THE ENDOGENOUS BACTERIOPHAGES OF STREPTO- COCCUS PYOGENES STRAIN SF370 DISCOVERED BY WHOLE GENOME SEQUENCING: IMPLICATIONS FOR PATHOGENESIS

William McShan

9:20 – 9:40 a.m.

PHYLOGENETIC RELATIONSHIP BETWEEN COLIPHAGE T4 AND VIBRIOPHAGE KVP40

Shigenobu Matsuzaki

9:40 – 10:00 a.m.

DISCOVERY OF PERTUSSIS TOXIN SEQUENCES PRESENT IN BORDETELLA AVIUM BACTERIOPHAGES

Derrick Lenz et al.